The options when you have two subs each with dual 4 ohm voice coils:
All in parallel: 1 ohm
all in series: 16 ohms
series the coils on each sub, then run the two subs in parallel: 4 ohms
I would usually suggest running the amp in 4 ohm mono for the best "performance". Running it in 1 ohm mono will provide more power, but usually the amp has less control of the speaker and will run much hotter in the process.
As with everything else, it is a tradeoff that you need to decide what you want.