I-drive is a good place since you are basically in the middle of everything. I would, if I were you, check out the outlet malls since they are right there, USF (Universal Sutdios Fla), Disney (of course) and if you are daring enough downtown Orlando.
There is really so much to do that 1 week wont be enough time to do it all. You need to figure out what is more important and go from there.
Heck you could spend a week at Disney alone and not see everything that they have to offer.
