Bridge the tweets into the bridged front channel (3ohm load) and bridge the mids into the bridged rear channel(2ohm load). That way depending on what deck you have and how you have it hooked up you can use the Xover adjustments on the deck until you get your x-over
The amp is rated 160x2 @ 4ohms so this will give you a 5ohm load total. 40w to each of the mids and probably around 35w to the tweets. hope this helps