Kimber is VERY nice (I personally prefer Wilson Combat for a .45), but if he's got a petite lady on his hands, the grip is going to feel like grabbing the thick end of a baseball bat.
A small-frame .45 is going to be somewhat of a hand-cannon for a smaller lady in terms of recoil, too.
I'm stereotyping here a bit, but I've ran into very few dainty ladies at the gun range that were slinging large-caliber, small-frame autos and for good reason...
If she's got the muscle, control and hands for such a piece, go for it.
