I'm on my 6th set of wheels of various sizes.
Most recenlty I went from 25lb+ 18" wheels to 15lb wheels.
The first time I took the car out, I was able to spin the wheels in 2nd with no problems whatsoever - which took effort with the 18s.
Pickup/acceleration was dramatically improved. Reducing weight in the car is one thing, reducing unsprung weight seems to be much more dramatic.