ATX, MTX, what are the symptoms, what kind of a driver are you (aggressive, non-aggressive), was it bought used, etc.?
The MTX-75 has seen it's fair share of problems. There are certain "weak links" in it, especially if driven a certain way. Syncros and selector forks tend to head south, differentials will totally fail given enough wheel-hop or type of jarring abuse on the tranny, cluthes will give up the ghost early if you "ride" the clutch too much...
...at least those seem to be the most common occurances of transmission failure that have crossed this board.
I honestly haven't heard of too many ATX failures, though that's probably due to the skew in enthusiasts here (most are "manual" lovers)...
More information, please.