Two ways are simple and straight fwd,,3 ways can be a pain i think.
I have just a 2 way system w/o eq, and it sounds awesome, as I got complimented today. ( I had the PG EQ230 ) powered up to make sure its working properly, and the guys at the shop said that the system sounds incredible given that I did everything by ear.
Just get good stuff and use common sense, and it should sound good,,,if you have an Alpine PXA-H600,,that would help as well