I have heard mixed results on the GIAC chips, they seem to still have some problems with there programming(Shuttering...etc) Although when they get everything straight should be a nice chip.
APR is a bit low on raw HP/TQ number when compared with the other chips. ALthough they have some very nice programming options/tools.
ABT would be one of my main choices. I have heard they make some serious hp/tq and the delivery is exactly like stock. Plus I hear it adapts!
MTM would be one of my main choices. Pascal is right about it requiring a highflow exhaust. Plus MTM is pretty expensive! One plus about this chip is they from what I hear Jo Hoppen has had a ton of experience programming stock Audi Chips and that he knows his stuff. The MTM chip is a bit more powerful than the ABT but they have different delivery's.
If I were to choose between the ABT and the MTM I would go ABT. The ABT/AMS acomplishes the nearly the same power as the MTM with much less boost. The APR is nice as well but from what I hear its a bit on the RAW side.
Here is a helpful review of the chips:
http://www.europeanspeed.com/shootout.htm (They are wrong about the AMS chip...I talked to AMS and they said their chip is actually an ABT chip modified to fit US specs Audi's...Go figure?)
Anyways good luck w/ your S4...Hopefully I'll be joining the ranks soon! (Within the next year)
Later