Don't underestimate presentation.
You have to be assertive when you prepare a CV, fill out an application or go for an interview.
When I was out of work a few years ago, I spent a good deal of time rewriting my CV and learning about interview skills so that I would be prepared and relaxed when the "big moment" came.
I also sent out dozens of applications, but I always followed up with the person hiring. It shows that you have a real interest in working there and that you have some character and will speak up for yourself. Otherwise you may end up as another name in a pile of applications.
Alot of people treat job prospects as a lottery, when it is actually a competition. If you're not ready, only pure luck will get you the job.
Look at website postings in the evening after you've done your real search during the day.
Cold call. Visit companies in person. Don't just look at places that you think "fit your profile".
Make a list of places to visit and set some goals.
Most of all, don't sell yourself short. Blow you're own horn and feel good about it.
Be positive about your prospects and good luck in your search.
