I got 45K out of my first set, and that was with one day spent on a track. The tread life rating is 300 which is the highest I have seen for high performance tires. Obviously autocrosses and and track days will take thousands of miles off the life in just minutes of use.
Daveandrews, you've had 4 alignments? I had my alignment check twice in 48k miles and I haven't needed yet. And that's in MI home of the '4 foot pothole in the middle of the interstate'.