Essentially that team will have little to no difficulty making the characters coming to life.
Each member has their own specialty. In the end I'd say if Venom has more scenes than Sandman, that the CG render time will be high and therefore, a huge priority to get it done first.
Sandman's FX will most likely be preset plugins, which are difficult to get right because they involve the most tweaking.
Combine the two into an already huge CG city, etc. It's actually tough to call. In the end I still think venoms' 3D model will be hardest to work with, and priority.