Well, my '98 has 430,000km (about 267,000 miles), and she's been a treat. I've done a lot of highway and city driving.
The only 'major' item that I've had to replace is the VCT solenoid a year ago, and an alternator... (whoopie...)
There's always the stuff like )2 sensors, PCV valves and such, but I consider those to be maintenance...
Other than that, follow the maintenance schedule, change the timing belt (and water pump!) when necessary (anywhere from 60K km to 100K km).