I highly doubt it'd be unsafe because the head of the bolt is on the bottom, as long as it's torqued down right. Dab some loc tite on there just to be safe if one would be really that worried about it.
2005 Ford F150 SuperCab FX4
1964 Chevrolet Impala SS
1998 CSVT: 354HP/328TQ @ 10 psi, now gone
