Don't follow the vehicle infront of you too close, so you can avoid road debris or anything that they run over. Watch out for anything hairy that you will have to avoid. If anyone rearends you, they are following too close and are at fault in almost any situation.
Honestly, I don't see any real problems until you see residential areas w/ mega speed bumps or deep gutters. You'll be going slow anyway, so it shouldn't be a huge deal....just a minor PITA.
2005 Ford F150 SuperCab FX4
1964 Chevrolet Impala SS
1998 CSVT: 354HP/328TQ @ 10 psi, now gone