Poor Man's Pressurized Fuel Injector Cleaning:
Normal disclaimers apply (take your own chances; your mileage may vary), but it has helped me.
I thought of this while changing the fuel filter my '86 Mustang 5.0:
Basically, I filled the new fuel filter with fuel injector cleaner (Berryman's is my favorite for this). The engine will get a short period of pure injector cleaner just after starting.
I used a syringe to fill the filter (so I know I used 120ml of fluid). My filter shipped with covers on each end of the filter; I left one cover on while filling the filter.
Surprisingly, I only spilled a few drops of fluid while installing the full filter. I had to hold my thumb over the end of the filter until pushing the hose on, but it worked pretty well. I then pulled the cover off the other end and repeated the process. A little tricky, but not difficult.
As it turns out, my Mustang had a slightly drippy injector that caused an unstable idle. Running the pure cleaner through the system made an immediate, noticeable difference. This was after adding numerous bottles of various cleaners to the tank; they were simply too diluted by the time they reached the injector to make a difference in my case.
This technique won't solve everyone's problems, but it can make a difference in a bolderline case where adding the cleaner to the tank isn't quite enough to do the trick.
Phil