A plenum is a passage intended for airflow.
The intake plenum is everything between the throttle body and the MAF. On Zetecs and my Crown Vic this includes a resonator to smooth airflow and dampen sound. The Duratec only has a small one consisting of the pleated rubber hose and the connections to the PCV system and IAC. Any unmetered air entering after the MAF will cause a lean condition.
Fuel system cleaner is usually not a problem. If fuel pressure is suspected put a fuel pressure gauge on it.